Heather Chandler
Associate Professor
Contact Information
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Postal address:
338 W 10th Ave Room 562 Fry Hall Columbus, OH 43210
Biographical narrative
Dr. Heather Chandler received her PhD in veterinary biosciences from The Ohio State University evaluating epithelial-mesenchymal transition in the cornea and lens. She continued her training in the College of Veterinary Medicine as a post-doctoral researcher prior to co-managing core facilities in Veterinary Clinical Sciences. Dr. Chandler has been faculty in the College of Optometry since 2007.
Dr. Chandler's primary research focus examines the mechanisms by which re-epithelialization and fibrosis occur within cataracts, secondary cataracts, and in the cornea. Current research includes evaluating specific protein pathways to inhibit the vascular and fibrotic response in the cornea following injury and reducing secondary cataract formation through either surgical or pharmacologic intervention. The overall goal of her lab is to clinically apply bench-top research findings to the bedside.
Journal articles
- Chandler, H. L., Tan, T., Yang, C., Gemensky-Metzler, A. J., Wehrman, R. F., Jiang, Q., . . . Ma, J. (2019). MG53 promotes corneal wound healing and mitigates fibrotic remodeling in rodents. Communications Biology, 2(1). doi:10.1038/s42003-019-0316-7
- Wehrman, R. F., Gemensky-Metzler, A. J., Zibura, A. E., Nyhart, A. B., & Chandler, H. L. (2017). Objective evaluation of the systemic effects of topical application of 1% atropine sulfate ophthalmic solution in healthy horses. Journal of the American Veterinary Medical Association, 251(11), 1324-1330. doi:10.2460/javma.251.11.1324
- Haworth, K. M., & Chandler, H. L. (2017). Seasonal Effect on Ocular Sun Exposure and Conjunctival UV Autofluorescence. Optometry and Vision Science, 94(2), 219-228. doi:10.1097/OPX.0000000000001014
- Simeone, C. A., Colitz, C. M. H., Colegrove, K. M., Field, C. L., Rios, C., Chandler, H. L., & Johnson, S. P. (2016). Subconjunctival antimicrobial poloxamer gel for treatment of corneal ulceration in stranded California sea lions (Zalophus californianus). Veterinary Ophthalmology. doi:10.1111/vop.12447
- Induction of posterior capsule opacification by hyaluronic acid in an ex vivo model. (2012). Investigative ophthalmology & visual science, 53(4).
- The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model (2010). Molecular Vision, 16.
- In vivo effects of tetracycline on canine refractory ulcers (2010). Journal of the American Veterinary Medical Association, 4(237).
- All-trans retinoic acid regulates Cx43 expression, gap junction communication and differentiation in lens epithelial cells (2010). Current Eye Research, 35(8).
- Distribution and amount of pigment within the ciliary body and iris or dogs with blue and brown irides (2010). Veterinary Ophthalmology, 2(13).
- Immunohistochemical analysis of ocular hemangiomas and hemangiosarcomas in dogs. (2009). Veterinary Ophthalmology, 12(2).
- The acute cutaneous inflammatory response is attenuated in Slug-knockout mice (2008). Laboratory Investigation, 88(8). doi:10.1038/labinvest.2008.37
- Modulation of matrix metalloproteinases by ultraviolet radiation in the canine cornea (2008). Veterinary Ophthalmology, 11(3).
- Effect of grape polyphenols on oxidative stress in canine lens epithelial cells. (2008). American Journal Of Veterinary Research, 69(1).
- Role of bacteria in the pathogenesis of recurrent uveitis in horses from the southeastern United States. (2008). American Journal Of Veterinary Research, 69(10).
- Ultraviolet radiation-induced corneal degeneration in 129 mice. (2007). Toxicologic Pathology, 35(6).
- Ultraviolet radiation-induced corneal degeneration in 129 mice (2007). Toxicologic Pathology, 35(6). doi:10.1080/01926230701584197
- The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog (2007). Experimental Eye Research, 84(3). doi:10.1016/j.exer.2006.10.010
- Evaluation of advanced glycation end-products in diabetic and inherited canine cataracts (2007). Graefe's Archive for Clinical and Experimental Ophthalmology, 245(2). doi:10.1007/s00417-006-0293-7
- Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition. (2007). Molecular Vision, 13.
- Snai2 expression enhances ultraviolet radiation-induced skin carcinogenesis. (2007). The American Journal Of Pathology, 171(5).
- The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog. (2007). Experimental Eye Research, 84(3).
- Evaluation of advanced glycation end-products in diabetic and inherited canine cataracts. (2007). Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie, 245(2).
- Immunohistochemical properties of ocular adenomas, adenocarcinomas and medulloepitheliomas. (2006). Veterinary Ophthalmology, 9(6).
- Molecular biology for the clinician: Understanding current methods (2006). Journal of the American Animal Hospital Association, 42(5).
- Ultraviolet irradiation up-regulates telomerase transcription and activity in lens epithelial cells. (2006). Veterinary Ophthalmology, 9(5).
- Expression and characterization of the catalytic subunit of telomerase in normal and cataractous canine lens epithelial cells. (2006). Molecular Vision, 12.
- Analysis of transport and cytotoxicity of topical nalbuphine solution in corneal cells (n.d.). American Journal of Veterinary Research.
Honors
- First Place, Research Day, 20060101 - 20060101
- First Place, Distinguished Graduate Seminar Award, 20060101 - 20060101
- First Place, Research Day, 20050101 - 20050101
- First Place, Distinguished Graduate Seminar Award, 20040101 - 20040101
- Travel Award to the 32nd Annual American Society for Photobiology Meeting, 20040101 - 20040101
- First Place, Distinguished Graduate Seminar Award, 20030101 - 20030101
Books
- Epithelial-Mesenchymal Transition in the Anterior Segment of the Eye (2006). . The Ohio State University, College of Veterinary Medicine.
Presentations
- Bringing Research from the Lab Bench to the Public: A Challenge to Women in Science (n.d.). In Prevent Blindness Ohio.
- Effects of AquaLase capsule washing on lens epithelial cells and PCO formation in vitro following phacoemulsification (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- UV absorption of contact lenses: it significance on the anterior segment of the eye (n.d.). In Scientific Symposium: Ultraviolet Radiation and its Effects on the Human Eye.
- Impact of Nalbuphine on canine corneal cells in vitro (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- Effects of Cyclosporin A on in vitro lens epithelial cell migration, proliferation, and PCO formation (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- Effects of hyaluronic acid on canine lens epithelial cells in vitro (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- Morphologic characterization of UV-induced degeneration of the cornea in wild type 129 mice (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- COX-2 expression in canine lens epithelial cells (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- The effect of grapeseed extract on canine lens epithelial cells (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- Phosphorylation of Telomerase and Estrogen Receptor-Alpha by AKT in Cataracts (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- Inhibition of Akt regulates telomerase activity inlens epithelial cells (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- The Role of Tetracyclines in Healing of Canine Refractory Ulcers (n.d.). In The Ohio State University, College of Veterinary Medicine Research Day.
- Ultraviolet radiation induction of MMP activity (n.d.). In Annual Meeting of the American Society for Photobiology.
Abstracts
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Effect of modified cyclosporine A on lens epithelial cell and corneal endothelial cell viabilityRIV Author(s): Lutz EA, Wilkie DA, Gemensky-Metzler AJ, Chandler HLPublication Status: PublishedPublication date: March 2012Publisher: Cadmus, MarylandVolume: 53RIV Pages: E-abstract 6692Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: In vitro comparison of meibum and cholesteryl ester films using high resolution color microscopy (HRCM)RIV Author(s): King-Smith PE, Chandler HL, Reuter KSPublication Status: PublishedPublication date: March 2012Publisher: Cadmus, MarylandVolume: 53RIV Pages: E-abstract 616Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 25
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Impact of modified cyclosporine A on lens epithelial cell and corneal endothelial viabilityRIV Author(s): Lutz EA, Wilkie DA, Gemensky-Metzler AJ, Chandler HLPublication Status: PublishedPublication date: December 2011Publisher: Wiley-Blackwell, New JerseyType of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Lens epithelial cell protection from ultraviolet radiation using grape seed extractRIV Author(s): Chandler HL, Colitz CMHPublication Status: PublishedPublication date: April 2011Publisher: Cadmus, MarylandVolume: 52RIV Pages: E-abstract 1555Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 80
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Protection of canine lens epithelial cells from ultraviolet radiation induced apoptosis with grape seed extractRIV Author(s): Chandler HLPublication Status: PublishedPublication date: December 2010Publisher: Wiley-Blackwell, New JerseyVolume: 13RIV Pages: 417Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 100
- Title of Publication: Veterinary OphthalmologyTitle of Entry: The effects of hyaluronic acid on lenticular epithelial migration in vitroRIV Author(s): Haeussler DJ, Lutz EA, Wilkie DA, Gemensky-Metzler AJ, Chandler HLPublication Status: PublishedPublication date: December 2010Publisher: Wiley-Blackwell, New JerseyVolume: 13RIV Pages: 414Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: The effects of AquaLase capsular washing on lens epithelial cells and PCO formation in vitro following phacoemulsificationRIV Author(s): Lutz EL, Wilkie DA, Gemensky-Metzler AJ, Chandler HLPublication Status: PublishedPublication date: December 2010Publisher: Wiley-Blackwell, New JerseyVolume: 13RIV Pages: 414Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Optimization of methods for analysis of high molecular weight tear glycoproteins and tear mucinsRIV Author(s): Ramamoorthy P, Thangavelu M, Chandler HL, Nichols JJPublication Status: PublishedPublication date: April 2010Publisher: Cadmus, MarylandVolume: 51RIV Pages: E-Abstract 4188Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 30
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Effects of hyaluronic acid on lens epithelial cell migration and proliferationRIV Author(s): Chandler HL, Haeussler DJ, Lutz EA, Wilkie DA, Metzler AGPublication Status: PublishedPublication date: April 2010Publisher: Cadmus, MarylandVolume: 51RIV Pages: E-Abstract 6357Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Expression of matrix metalloproteinases in feline eyes with uveitis and lens luxationsRIV Author(s): Broadwater JJ, Colitz CMH, Dubielzig RR, Carastro SM, Chandler HLPublication Status: PublishedPublication date: April 2010Publisher: Cadmus, MarylandVolume: 51RIV Pages: E-Abstract 5231Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Expression of matrix metalloproteinases in feline eye with uveitis and lens luxationsRIV Author(s): Broadwater JJ, Colitz CMH, Dubielzig RR, Carastro SM, Chandler HLPublication Status: PublishedPublication date: December 2009Publisher: Wiley-Blackwell, New JerseyVolume: 6RIV Pages: 407Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: The effects of topical nalbuphine on canine corneal cells in vitroRIV Author(s): Spatola RA, Thangavelu M, Chandler HLPublication Status: PublishedPublication date: December 2009Publisher: Wiley-Blackwell, New JerseyVolume: 6RIV Pages: 397Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: UV-absorbing contact lenses mediate UV-induced damage to the anterior segmentRIV Author(s): Chandler HL, Reuter KS, Sinnott LT, Nichols JJPublication Status: PublishedPublication date: December 2009Publisher: Wiley-Blackwell, New JerseyVolume: 6RIV Pages: 392Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: Journal of the British Contact Lens AssociationTitle of Entry: UV-absorbing silicone hydrogens mediate UV-induced damage to the anterior segmentRIV Author(s): Nichols JJ, Chandler HL, Reuter KS, Sinnott LTPublication Status: PublishedPublication date: June 2009Publisher: Elsevier, PennsylvaniaType of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Prevention of UV-induced damage to the anterior segment using UV-absorbing contact lensesRIV Author(s): Chandler HL, Reuter KS, Sinnott LT, Nichols JJPublication Status: PublishedPublication date: April 2009Publisher: Cadmus, New JerseyVolume: 50RIV Pages: ARVO E-Abstract 4783Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Examination of human meibum collection and extraction techniquesRIV Author(s): Haworth KM, Nichols JJ, Thangavelu M, Sinnott LT, Chandler HL, Nichols KKPublication Status: PublishedPublication date: April 2009Publisher: Cadmus, MarylandVolume: 50RIV Pages: ARVO E-Abstract 2544Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 30
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Evaluation of tear film protein extraction buffersRIV Author(s): Powell DR, Thangavelu M, Chandler HL, Nichols KK, Nichols JJPublication Status: PublishedPublication date: April 2009Publisher: Cadmus, MarylandVolume: 50RIV Pages: ARVO E-Abstract 5628Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 30
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Immunohistochemical analysis of canine and feline uveal melanomasRIV Author(s): Acevedo MC, Colitz CMH, Barden CA, Newkirk KM, Kusewitt DF, Dubielzig RR, Chandler HLPublication Status: PublishedPublication date: December 2008Publisher: Wiley-Blackwell, New JerseyVolume: 11RIV Pages: 428Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 30
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Selenium functionalized intraocular lenses inhibit posterior capsule opacification (PCO) in an ex vivo canine lens capsule bag assayRIV Author(s): Pot SA, Chandler HL, Colitz CMH, Bentley E, Dubielzig RR, Mosley TS, Reid TW, Murphy CJPublication Status: PublishedPublication date: December 2008Publisher: Wiley-Blackwell, New JerseyVolume: 11RIV Pages: 421Type of Work: AbstractReviewed Item?: trueType of Review: Peer...
- Title of Publication: Veterinary OphthalmologyTitle of Entry: In vivo effects of tetracyclines on healing of canine refractory corneal ulcersRIV Author(s): Chandler HL, Bras ID, Robbin-Webb TE, Saville WJA, Gemensky-Metzler AJ, Colitz CMHPublication Status: PublishedPublication date: December 2008Publisher: Wiley-Blackwell, New JerseyVolume: 11RIV Pages: 425Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Association between papillomavirus and the development of canine ocular squamous papillomasRIV Author(s): Klemas AS, Dubielzig RR, Chandler HLPublication Status: PublishedPublication date: December 2008Publisher: Wiley-Blackwell, New JerseyVolume: 11RIV Pages: 428Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Differences in pigment distribution within the ciliary body of blue-eyed and brown-eyed dogsRIV Author(s): Newkirk KM, Haines DK, Calvarese ST, Esson DW, Chandler HLPublication Status: PublishedPublication date: December 2008Publisher: Wiley-Blackwell, New JerseyVolume: 11RIV Pages: 428Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 30
- Title of Publication: Optometry and Vision ScienceTitle of Entry: Tear protein extraction from Schirmer stripsRIV Author(s): Paulette C, Chandler HL, Nichols KKPublication Status: PublishedPublication date: November 2008Publisher: Wolters Kluwer, PennsylvaniaRIV Pages: E-abstract 80022Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 30
- Title of Publication: Optometry and Vision ScienceTitle of Entry: Evaluation of tear protein collection and extraction methods in soft contact lens wearersRIV Author(s): Powell DR, Chandler HL, Nichols KK, Nichols JJPublication Status: PublishedPublication date: November 2008Publisher: Wolters Kluwer, PennsylvaniaRIV Pages: E-abstract 85318Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 30
- Title of Publication: Optometry and Vision ScienceTitle of Entry: The impact of UV-blocking hydrogel polymers on the prevention of UV-induced ophthalmic damage.RIV Author(s): Chandler HL, Reuter KS, Nichols JJPublication Status: PublishedPublication date: November 2008Publisher: Wolters Kluwer, PennsylvaniaRIV Pages: E-abstract 80104Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: Optometry and Vision ScienceTitle of Entry: Tear film proteomic analysis in keratoconusRIV Author(s): Pannebaker C, Chandler HL, Nichols JJPublication Status: PublishedPublication date: November 2008Publisher: Wolters Kluwer, PennsylvaniaRIV Pages: E-abstract 80027Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 30
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Immunohistochemical analysis of uveal melanomas in cats and dogsRIV Author(s): Chandler HL, Barden CA, Newkirk KM, Kusewitt DF, Colitz CMH, Dubielzig RRPublication Status: PublishedPublication date: April 2008Publisher: Cadmus, MarylandVolume: 48RIV Pages: ARVO E-Abstract 70Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 30
- Title of Publication: Veterinary Ophthalmology - European College of Veterinary OphthalmologistsTitle of Entry: Selenium functionalized intraocular lenses inhibit posterior capsular opacification (PCO) in ex vivo canine lens capsular bag assayRIV Author(s): Pot SA, Chandler HL, Colitz CMH, Bentley E, Dubielzig RR, Mosley TS, Reid TW, Murphy CJPublication Status: PublishedPublication date: January 2008Publisher: Wiley-Blackwell, New JerseyType of Work: AbstractReviewed Item?: trueType of...
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: The effect of grape proanthocyanidins on free radical formation and oxidative stress markers in canine lens epithelial cellsRIV Author(s): Colitz CMH, Barden CA, Chandler HLPublication Status: PublishedPublication date: April 2007Publisher: Cadmus, MarylandVolume: 47RIV Pages: E-Abstract 2430Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Bacteria in eyes with chronic recurrent uveitis in horses from southwestern United StatesRIV Author(s): Gilger BC, Salmon JH, Barden CA, Chandler HL, Wendt J, Colitz CMHPublication Status: PublishedPublication date: April 2007Publisher: Cadmus, MarylandVolume: 47RIV Pages: E-Abstract 2626Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 30
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Morphologic characterization of UV-induced degeneration of the cornea in wild type 129 miceRIV Author(s): Chandler HL, Newkirk KM, Parent AE, Colitz CMH, Wilkie DA, Kusewitt DFPublication Status: PublishedPublication date: April 2007Publisher: Cadmus, MarylandVolume: 47RIV Pages: E-Abstract 3504Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 60
- Title of Publication: Veterinary Ophthalmology - European Conference of Veterinary OphthalmologyTitle of Entry: Bacteria in eyes with chronic recurrent uveitis in horses from southeastern United StatesRIV Author(s): Gilger BC, Salmon JH, Barden CA, Chandler HL, Wendt J, Colitz CMHPublication Status: PublishedPublication date: January 2007Publisher: Wiley-Blackwell, New JerseyType of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 30
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Expression of cyclin dependent kinase inhibitor for p15INK4B in canine refractory ulcersRIV Author(s): Hodgson MJ, Chandler HL, Miller WW, Colitz CMHPublication Status: PublishedPublication date: December 2006Publisher: Wiley-Blackwell, New JerseyVolume: 9RIV Pages: 419Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Modulation of matrix metalloproteinases by ultraviolet radiation in the canine corneaRIV Author(s): Chandler HL, Kusewitt DF, Colitz CMHPublication Status: PublishedPublication date: December 2006Publisher: Wiley-Blackwell, New JerseyVolume: 9RIV Pages: 423Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: Veterinary OphthalmologyTitle of Entry: The effect of grape proanthocyanidins on oxidative stress and migration in canine lens epithelial cellsRIV Author(s): Chandler HL, Barden CA, Lu P, Colitz CMHPublication Status: PublishedPublication date: December 2006Publisher: Wiley-Blackwell, New JerseyVolume: 9RIV Pages: 423Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Morphologic Characterization of UV-induced degeneration of the cornea and lens in wild type 129 miceRIV Author(s): Newkirk KM, Chandler HL, Parent AE, Colitz CMH, Wilkie DA, Kusewitt DFPublication Status: PublishedPublication date: December 2006Publisher: Wiley-Blackwell, New JerseyVolume: 9RIV Pages: 423Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Ultraviolet irradiation up-regulates telomerase transcriptionRIV Author(s): Colitz CMH, Barden CA, Chandler HL, Lu PPublication Status: PublishedPublication date: April 2006Publisher: Cadmus, MarylandVolume: 46RIV Pages: E-Abstract 4082Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: The effect of grapeseed extract on canine lens epithelial cellsRIV Author(s): Barden CA, Chandler HL, Lu P, Colitz CMHPublication Status: PublishedPublication date: April 2006Publisher: Cadmus, MarylandVolume: 46RIV Pages: E-Abstract 2541Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: COX-2 expression in canine lens epithelial cellsRIV Author(s): Chandler HL, Barden CA, Lu P, Elligott C, Colitz CMHPublication Status: PublishedPublication date: April 2006Publisher: Cadmus, MarylandVolume: 46RIV Pages: E-Abstract 2538Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Resolution of spontaneous epithelial erosions after corneal debridement wounding in mice is not altered by treatment of mice with oral doxycyclineRIV Author(s): Stepp M, Ghosh SP, Liu Y, Jurjus RA, Chandler HL, Colitz CMH, Kusewitt DKPublication Status: PublishedPublication date: April 2006Publisher: Cadmus, MarylandVolume: 46RIV Pages: E-Abstract 2758Type of Work: AbstractReviewed Item?: trueType of Review:...
- Title of Publication: Veterinary OphthalmologyTitle of Entry: The effect of phosphorylated Akt inhibition on posterior capsular opacification in the canine lensRIV Author(s): Robbin TE, Chandler HL, Barden CA, Kulp SK, Chen C, Wyman M, Bras ID, Wilkie DA, Gemensky-Metzler AL, Colitz CMHPublication Status: PublishedPublication date: December 2005Publisher: Wiley-Blackwell, New JerseyVolume: 8RIV Pages: 448Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of...
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Estrogen localization and local synthesis of estrogen by cataractous LECRIV Author(s): Colitz CMH, Chandler HL, Lu P, Sugimoto Y, Barden CA, Metzler AJG, Wilkie DA, Bras ID, Kuonen VJ, Robbin TEPublication Status: PublishedPublication date: December 2005Publisher: Wiley-Blackwell, New JerseyVolume: 8RIV Pages: 440Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Expression of cyclin dependent kinase inhibitor p15INK4B in canine refractory corneal ulcersRIV Author(s): Hodgson MJ, Miller WW, Colitz CMH, Chandler HLPublication Status: PublishedPublication date: December 2005Publisher: Wiley-Blackwell, New JerseyVolume: 8RIV Pages: 443Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Markers of epithelial-mesenchymal transition during cataractogenesisRIV Author(s): Chandler HL, Barden CA, Colitz CMH, Kusewitt DKPublication Status: PublishedPublication date: December 2005Publisher: Wiley-Blackwell, New JerseyVolume: 8Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: The role of tetracyclines in healing of canine refractory ulcersRIV Author(s): Chandler HL, Colitz CMH, Miller WW, Kusewitt DFPublication Status: PublishedPublication date: April 2005Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2597Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Phosphorylation of telomerase and estrogen receptor-alpha by AKT in cataractsRIV Author(s): Barden CA, Chandler HL, Lu P, Colitz CMHPublication Status: PublishedPublication date: April 2005Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2866Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Epithelial-mesenchymal transformation in canine cataractogenesisRIV Author(s): Kusewitt DF, Chandler HL, Colitz CMHPublication Status: PublishedPublication date: April 2005Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2876Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Estrogen localization and local synthesis of estrogen by cataractous LECRIV Author(s): Colitz CMH, Chandler HL, Lu P, Sugimoto Y, Barden CA, Metzler AJG, Wilkie DA, Bras ID, Kuonen VJ, Robbin TPublication Status: PublishedPublication date: April 2005Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2893Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort:...
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Over-expression of ER alpha in Canine Lens Epithelial Cells Results in Up-Regulation of TERT and TRRIV Author(s): Lu P, Barden CA, Chandler HL, Sugimoto Y, Colitz CMHPublication Status: PublishedPublication date: April 2005Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2894Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: The effect of phosphorylated Akt inhibition on posterior capsular opacification in the canine lensRIV Author(s): Robbin TE, Chandler HL, Barden CA, Kulp SK, Chen C, Wyman M, Wilkie DA, Gemensky-Metzler AJ, Bras ID, Colitz CMHPublication Status: PublishedPublication date: April 2005Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2867Type of Work: AbstractReviewed Item?: trueType of Review: Peer...
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Phosphorylation of telomerase and estrogen receptor-alpha by Akt in cataractsRIV Author(s): Colitz CMH, Barden CA, Chandler HL, Lu P, Metzler AG, Wilkie DA, Bras ID, Kuonen VJPublication Status: PublishedPublication date: December 2004Publisher: Wiley-Blackwell, New JerseyVolume: 7RIV Pages: 445Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 50
- Title of Publication: Veterinary OphthalmologyTitle of Entry: Role of tetracyclines in healing of canine refractor corneal ulcersRIV Author(s): Chandler HL, Colitz CMH, Kusewitt DFPublication Status: PublishedPublication date: December 2004Publisher: Wiley-Blackwell, New JerseyVolume: 7RIV Pages: 445Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: paperPercent Authorship: 75
- Title of Publication: International Congress of Eye ResearchTitle of Entry: Telomerase interacts with estrogen receptor alpha in cataractous LECRIV Author(s): Colitz CMH, Barden CA, Lu P, Chandler HLPublication Status: PublishedPublication date: August 2004Publisher: Elsevier, Pennsylvania, United StatesType of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Ultraviolet irradiation induction of MMP activity in the corneaRIV Author(s): Chandler HL, Kusewitt DF, Colitz CMHPublication Status: PublishedPublication date: April 2004Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 3756Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Estrogen receptor-alpha expression in canine cataractsRIV Author(s): Colitz CMH, Barden CA, Chandler HL, Lu P, Metzler AJG, Wilkie DA, Bras ID, Sugimoto Y, Mauger TM, Lembach RGPublication Status: PublishedPublication date: April 2004Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 2649Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship...
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Evaluation of advanced glycation end-products in diabetic and inherited canine cataractsRIV Author(s): Bras ID, Chandler HL, Wilkie DA, Gemensky AJ, Kuonen VJ, Koyama H, Colitz CMHPublication Status: PublishedPublication date: April 2004Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 1690Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent...
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Inhibition of Akt regulates telomerase activity in lens epithelial cellsRIV Author(s): Barden CA, Chandler HL, Colitz CMHPublication Status: PublishedPublication date: April 2004Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 384Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 50
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: The Slug transcription factor modulates corneal epithelial cell migrationRIV Author(s): Chandler HL, Kusewitt DF, Colitz CMHPublication Status: PublishedPublication date: April 2004Publisher: Cadmus, MarylandVolume: 45RIV Pages: E-Abstract 3759Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
- Title of Publication: Investigative Ophthalmology and Visual ScienceTitle of Entry: Enhanced protease production in refractory corneal ulcersRIV Author(s): Chandler HL, Kusewitt DF, Colitz CMHPublication Status: PublishedPublication date: April 2003Publisher: Cadmus, MarylandVolume: 44RIV Pages: E-Abstract 914Type of Work: AbstractReviewed Item?: trueType of Review: Peer-ReviewDescription of Effort: posterPercent Authorship: 75
