Timothy Plageman

Assistant Professor

Contact Information

Postal address: 
338 W 10th Ave Room 460 Columbus, OH 43210

Journal articles

  • Muccioli, M., Qaisi, D., Herman, K., & Plageman, T. F. (2016). Lens placode planar cell polarity is dependent on Cdc42-mediated junctional contraction inhibition. DEVELOPMENTAL BIOLOGY, 412(1), 32-43. doi:10.1016/j.ydbio.2016.02.016
  • Loebel, D. A. F., Plageman, T. F., Tang, T. L., Jones, V. J., Muccioli, M., & Tam, P. P. L. (2016). Thyroid bud morphogenesis requires CDC42-and SHROOM3-dependent apical constriction. BIOLOGY OPEN, 5(2), 130-139. doi:10.1242/bio.014415
  • Epithelial Morphogenesis: The Mouse Eye as a Model System (2015). NEURAL CREST AND PLACODES, 111. doi:10.1016/bs.ctdb.2014.11.011
  • Epithelial morphogenesis: the mouse eye as a model system. (2015). Current topics in developmental biology, 111. doi:10.1016/bs.ctdb.2014.11.011
  • The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice (2014). BIOLOGY OPEN, 3(9). doi:10.1242/bio.20147450
  • Das, D., Zalewski, J. K., Mohan, S., Plageman, T. F., VanDemark, A. P., & Hildebrand, J. D. (2014). The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice. BIOLOGY OPEN, 3(9), 850-860. doi:10.1242/bio.20147450
  • p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis (2014). DEVELOPMENT, 141(16). doi:10.1242/dev.107433
  • Lang, R. A., Herman, K., Reynolds, A. B., Hildebrand, J. D., & Plageman, T. F. (2014). p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. DEVELOPMENT, 141(16), 3177-3187. doi:10.1242/dev.107433
  • Plageman, T. F., & Lang, R. A. (2012). Generation of an Rx-tTA: TetOp-Cre Knock-In Mouse Line for Doxycycline Regulated Cre Activity in the Rx Expression Domain. PLOS ONE, 7(11), 6 pages. doi:10.1371/journal.pone.0050426
  • A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination (2011). DEVELOPMENT, 138(23). doi:10.1242/dev.067868
  • Plageman, T. F., Chauhan, B. K., Yang, C., Jaudon, F., Shang, X., Zheng, Y., . . . Lang, R. A. (2011). A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination. DEVELOPMENT, 138(23), 5177-5188. doi:10.1242/dev.067868
  • Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis (2011). DEVELOPMENTAL BIOLOGY, 357(1). doi:10.1016/j.ydbio.2011.06.027
  • Plageman, T. F., Zacharias, A. L., Gage, P. J., & Lang, R. A. (2011). Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis. DEVELOPMENTAL BIOLOGY, 357(1), 227-234. doi:10.1016/j.ydbio.2011.06.027
  • Plageman, T. F., Chung, M. -I., Lou, M., Smith, A. N., Hildebrand, J. D., Wallingford, J. B., & Lang, R. A. (2010). Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination. DEVELOPMENT, 137(3), 405-415. doi:10.1242/dev.045369
  • Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination (2010). DEVELOPMENT, 137(3). doi:10.1242/dev.045369
  • Plageman, T. F., & Lang, R. A. (2009). Lens pit morphogenesis requires epithelial cell shape changes mediated by Shroom3. DEVELOPMENTAL BIOLOGY, 331(2), 447. doi:10.1016/j.ydbio.2009.05.225
  • Plageman, T. F., & Yutzey, K. E. (2006). Microarray analysis of Tbx5-induced genes expressed in the developing heart. DEVELOPMENTAL DYNAMICS, 235(10), 2868-2880. doi:10.1002/dvdy.20923
  • Plageman, T. F., & Yutzey, K. E. (2005). T-Box genes and heart development: Putting the "T" in HearT. DEVELOPMENTAL DYNAMICS, 232(1), 11-20. doi:10.1002/dvdy.20201
  • Plageman, T. F., & Yutzey, K. E. (2004). Differential expression and function of Tbx5 and Tbx20 in cardiac development. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(18), 19026-19034. doi:10.1074/jbc.M314041200
  • Loṕez-Escobar, B., Caro-Vega, J. M., Vijayraghavan, D. S., Plageman, T. F., Sanchez-Alcazar, J. A., Moreno, R. C., . . . Ybot-Gonzaĺez, P. (2018). The non-canonical Wnt-PCP pathway shapes the mouse caudal neural plate. Development (Cambridge), 145(9). doi:10.1242/dev.157487
  • Kaya, N., Alsagob, M., D'Adamo, M. C., Al-Bakheet, A., Hasan, S., Muccioli, M., . . . Al-Owain, M. (2016). KCNA4 deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability. JOURNAL OF MEDICAL GENETICS, 53(11), 786-792. doi:10.1136/jmedgenet-2015-103637

Honors

  • Basil O’Connor Starter Scholar Research Award, 20140201 - 20160201

Presentations

  • Heimlich, D., Martin, J., & Plageman, T. (n.d.). Anisotropic lens fiber cell geometry is regulated by Shroom3 and Rho-kinase junctional contraction. In International Conference on the Lens.
  • Houssin, N., Herman, K., Yoon, S. O., & Plageman, T. (n.d.). Characterization epithelial cell rearrangements during lens placode invagination. In International Conference on the Lens.
  • Lens placode cell anisotropic geometry is mediated by planar polarized inhibition of junctional contraction during invagination. (n.d.). In Visual System Development Gordon Research Conference.
  • Planar polarized cell behaviors as a force for lens placode invagination (n.d.). In International Conference on the Lens.
  • Plageman, T. F. (2016). Anisotropic geometry of lens placode cells is mediated by planar polarized inhibition of junctional contraction during invagination.. In Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO). Seattle, WA. Retrieved from http://gateway.webofknowledge.com/
  • Plageman, T. F., Reynolds, A., & Lang, R. A. (2014). Junctional p120-catenin Recruitment of Shroom3 Facilitates Apical Constriction During Lens Pit Morphogenesis. Retrieved from http://gateway.webofknowledge.com/

Abstracts

  • Title of Publication: 2016 ARVO annual meetingTitle of Entry: Requirements for cellular folate during lens developmentRIV Author(s): Muccioli, M, et al.Publication Status: PublishedPublication date: May 2016Publisher: IOVS, Rockville, Maryland, United StatesVolume: 57Type of Work: AbstractReviewed Item?: falseDescription of Effort: Directed trainee composition and data generation (not peer reviewed).Percent Authorship: 100
  • Title of Publication: 2016 ARVO annual meetingTitle of Entry: Anisotropic geometry of lens placode cells is mediated by planar polarized inhibition of junctional contraction during invagination.RIV Author(s): Plageman, TF Jr.Publication Status: PublishedPublication date: May 2016Publisher: IOVS, Rockville, MarylandVolume: 57Type of Work: AbstractReviewed Item?: falseDescription of Effort: Composed and generated data (not peer reviewed).Percent Authorship: 100
  • Title of Publication: 2014 ARVO annual meetingTitle of Entry: Junctional p120-catenin Recruitment of Shroom3 Facilitates Apical Constriction During Lens Pit MorphogenesisRIV Author(s): Plageman, TF Jr, Reynolds AB, Lang, RAPublication Status: PublishedPublication date: April 2014Publisher: Investigative Ophthalmology and Visual Science, Rockville, Maryland, United StatesVolume: 55Type of Work: AbstractReviewed Item?: falseDescription of Effort: Composed and generated data (not peer reviewed...

Chapters

  • Chapter Title: Lens determination and inductionBook Title: Encyclopedia of the EyeRIV Chapter Authors: Plageman, TF Jr, Chauhan, BK, Lang, RARIV Editors: Dartt, DA, Beebe, DCPublication Status: PublishedPublication date: January 2010Publisher: Elsevier, Boston, United StatesEdition: 1stISBN-13: 9780123741981Reviewed Item?: trueType of Review: Editor-ReviewPercent Authorship: 100